IMSI (Intracytoplasmic Morphologically Selected Sperm Injection)

IMSI (Intracytoplasmic Morphologically Selected Sperm Injection)

What is IMSI?

Intracytoplasmic morphologically selected sperm injection (IMSI) is a technique used in IVF treatment to examine and select sperm using a high-magnification digital imaging microscope for microinjection into the egg.

What is the fertility treatment process?

Fertility treatment typically refers to medications that stimulate egg or sperm production, or procedures that involve the handling of eggs, sperm, or embryos. However, treating infertility goes beyond fertility treatments.

In conventional ICSI, the embryologist selects the most normal-looking motile sperm using a microscope that magnifies the sample up to 400 times. IMSI is a variation of ICSI that uses a high power light microscope (enhanced by digital imaging) to magnify the sperm sample over 6000 times. This allows the embryologist to detect subtle structural alterations in sperm that a normal microscope could not detect. Sperm are then selected which have the most normally-shaped nuclei.